Article ID Journal Published Year Pages File Type
341764 Schizophrenia Research 2006 5 Pages PDF
Abstract

Neuregulin 1 has been implicated as a susceptibility gene in schizophrenia. Several research groups have reported association with the 5′ end of the gene although no causative variant has been reported. We have investigated whether there is association with the 5′ end of the gene in Danish schizophrenia patients. We found that the at-risk haplotype initially reported in the Icelandic population was not found in significant excess (or = 1.4, p = 0.12). The haplotype structure in the Danish sample was similar to that of other reported in other Caucasian populations and highly different from that of Chinese.

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