Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3419220 | Revista Iberoamericana de Micología | 2007 | 4 Pages |
Abstract
Native valve endocarditis caused by Aspergillus spp. is an uncommon disease with a high mortality rate. Generally, Aspergillus is isolated from affected valve in post-mortem or biopsy specimens. However, its isolation from blood cultures is exceedingly rare. We report a case of fungal endocarditis in a native mitral valve with the isolation of Aspergillus fumigatus both in valve vegetation and in blood culture bottles. The patient underwent valve replacement and antifungal treatment with voriconazole and caspofungin, but he died on post-operative day 45 with disseminated aspergillosis confirmed by necropsy. Paradoxically, galactomannan antigen detection in serum was negative. This is the third case of Aspergillus endocarditis with positive blood culture reported in the literature.
Keywords
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Authors
Javier Pemán, Rebeca Ortiz, Faisa Osseyran, Carmen Pérez-Bellés, Marisa Crespo, Melitina Chirivella, Juan Frasquet, Anastasio Quesada, Emilia Cantón, Miguel Gobernado,