Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3422491 | Trends in Microbiology | 2008 | 8 Pages |
Abstract
HIV type 2 (HIV-2), a closely related retrovirus discovered a few years after HIV type 1, causes AIDS in only a minority of infected individuals. Determining why HIV-2 causes asymptomatic infection in most patients could further our understanding of HIV immunopathogenesis. Studies to date have suggested that both enhanced immune responses and lower viral replication could play a role. We summarize the important findings to date and highlight areas that warrant further exploration.
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Authors
Thushan I. de Silva, Matthew Cotten, Sarah L. Rowland-Jones,