| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 37285 | Trends in Biotechnology | 2012 | 7 Pages |
Abstract
Recent advances in cell reprogramming have permitted the development of different stem cell lines and specific differentiated cell types using distinct technologies. Cell reprogramming is largely mediated by DNA and RNA. In this review, we explore the RNA-mediated cell reprogramming to induce specific target cell generation including stem cells, brain cells and cardiac cells. The ability of RNA populations to produce direct cell to cell phenotypic conversion is called Transcriptome Induced PhenotypeRemodeling (TIPeR). The theory and utility of RNA use for cellular reprogramming is explored in this review.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Jai-Yoon Sul, Tae Kyung Kim, Jae Hee Lee, James Eberwine,