| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 37687 | Trends in Biotechnology | 2006 | 4 Pages |
Abstract
Bacillus anthracis is ideal for making biological weapons, but the licensed anthrax vaccine is unsuitable for widespread public administration. Recombinant subunit-vaccine candidates offer potential alternatives, and plant-based production systems facilitate the inexpensive bulking of target antigens. A recent report demonstrates expression of anthrax protective antigen in tobacco chloroplasts – this material is immunogenic and protective when injected into mice. Provided an economic purification scheme can be developed, this technology holds promise for an improved vaccine.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Stephen J. Streatfield,