| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4011960 | Experimental Eye Research | 2009 | 5 Pages |
Abstract
Primary open-angle glaucoma is recognized as a disease of aging, and studies show a relationship between aging and trabecular meshwork (TM) cell density. Human TM cell division occurs primarily in the anterior, non-filtering region. A commonly used glaucoma treatment, laser trabeculoplasty (LTP), triggers and increases cell division, as well as cell migration of these anterior TM cells. These freshly-divided migrating cells repopulate the burned laser sites, suggesting that they are stem cells. Several studies concerning this putative TM stem cell will be discussed.
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Authors
M.J. Kelley, A.Y. Rose, K.E. Keller, H. Hessle, J.R. Samples, T.S. Acott,