Article ID Journal Published Year Pages File Type
4012103 Experimental Eye Research 2009 14 Pages PDF
Abstract

The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype. This review covers the development and structure of the lens capsule, lens diseases associated with mutations in extracellular matrix genes and the role of the capsule in lens function including those proposed for visual accommodation, selective permeability to infectious agents, and cell signaling.

Related Topics
Life Sciences Immunology and Microbiology Immunology and Microbiology (General)
Authors
, ,