| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4112 | Biochemical Engineering Journal | 2009 | 9 Pages |
Abstract
A previously proposed model of a transketolase catalysed carbon–carbon bond formation reaction condensing β-hydroxypyruvate and glycolaldehyde to synthesise l-erythrulose has been extended to describe various modes of operation as an alternative to a batch process. The alternative continuous and fed-batch operations, with each substrate being fed separately and together have been analysed using the extended model. The analysis was carried out simulating the product concentration after a given time under defined process conditions. Comparison of product concentration and yield on catalyst as two process metrics were used to identify promising cases for further process development.
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Physical Sciences and Engineering
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Authors
N.A. Sayar, B.H. Chen, G.J. Lye, J.M. Woodley,