| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4176790 | Seminars in Pediatric Surgery | 2007 | 8 Pages |
Abstract
The maladaptive response of the pulmonary vasculature that occurs in patients with congenital diaphragmatic hernia significantly impacts outcome. Muscularized distal pulmonary arterioles inhibit the ability of the neonate to adjust to extrauterine circulation, resulting in severe pulmonary hypertension. This review summarizes the current state of knowledge regarding normal and abnormal development of the lung vascular system and identifies current and potential therapies directed toward preserving or restoring proper pulmonary vascular function.
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Authors
Doug Miniati,