Article ID Journal Published Year Pages File Type
423557 Electronic Notes in Theoretical Computer Science 2016 16 Pages PDF
Abstract

Gene tree correction has recently gained interest in phylogenomics, as it gives insights in understanding the evolution of gene families. Following some recent approaches based on leaf edit operations, we consider a variant of the problem where a gene tree is corrected by inserting leaves with labels in a multiset M. We show that the problem of deciding whether a gene tree can be corrected by inserting leaves with labels in M is NP-complete. Then, we consider an optimization variant of the problem that asks for the correction of a gene tree with leaves labeled by a multiset M′, with M′⊇M, having minimum size. For this optimization variant of the problem, we present a factor 2 approximation algorithm.

Related Topics
Physical Sciences and Engineering Computer Science Computational Theory and Mathematics