| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4361754 | Cell Host & Microbe | 2009 | 5 Pages |
Abstract
Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.
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Authors
Nicolas Legrand, Alexander Ploss, Rudi Balling, Pablo D. Becker, Chiara Borsotti, Nicolas Brezillon, Jennifer Debarry, Ype de Jong, Hongkui Deng, James P. Di Santo, Stephanie Eisenbarth, Elizabeth Eynon, Richard A. Flavell, Carlos A. Guzman,