Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
459 | Acta Biomaterialia | 2014 | 15 Pages |
Abstract
Spider silks have been a focus of research for almost two decades due to their outstanding mechanical and biophysical properties. Recent advances in genetic engineering have led to the synthesis of recombinant spider silks, thus helping to unravel a fundamental understanding of structure–function–property relationships. The relationships between molecular composition, secondary structures and mechanical properties found in different types of spider silks are described, along with a discussion of artificial spinning of these proteins and their bioapplications, including the role of silks in biomineralization and fabrication of biomaterials with controlled properties.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Olena Tokareva, Matthew Jacobsen, Markus Buehler, Joyce Wong, David L. Kaplan,