| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 468647 | Computer Methods and Programs in Biomedicine | 2016 | 12 Pages |
•A new web-based system for analysis and understanding of tear film images is presented.•The web application is easily accessible, scalable and efficient.•Two services are available: tear film classification and tear film maps.•Experimentation results demonstrated the adequacy of both services to support dry eye diagnosis.•New services can be continuously incorporated according to practitioners’ necessities.
Background and objectivesDry eye disease is a public health problem, whose multifactorial etiology challenges clinicians and researchers making necessary the collaboration between different experts and centers. The evaluation of the interference patterns observed in the tear film lipid layer is a common clinical test used for dry eye diagnosis. However, it is a time-consuming task with a high degree of intra- as well as inter-observer variability, which makes the use of a computer-based analysis system highly desirable. This work introduces iDEAS (Dry Eye Assessment System), a web-based application to support dry eye diagnosis.MethodsiDEAS provides a framework for eye care experts to collaboratively work using image-based services in a distributed environment. It is composed of three main components: the web client for user interaction, the web application server for request processing, and the service module for image analysis. Specifically, this manuscript presents two automatic services: tear film classification, which classifies an image into one interference pattern; and tear film map, which illustrates the distribution of the patterns over the entire tear film.ResultsiDEAS has been evaluated by specialists from different institutions to test its performance. Both services have been evaluated in terms of a set of performance metrics using the annotations of different experts. Note that the processing time of both services has been also measured for efficiency purposes.ConclusionsiDEAS is a web-based application which provides a fast, reliable environment for dry eye assessment. The system allows practitioners to share images, clinical information and automatic assessments between remote computers. Additionally, it save time for experts, diminish the inter-expert variability and can be used in both clinical and research settings.
