Article ID Journal Published Year Pages File Type
4753678 Journal of Biotechnology 2017 4 Pages PDF
Abstract

•We report the first complete genome sequence of Streptomyces griseochromogenes.•S. griseochromogenes ATCC 14511T is a type producer of nucleoside antibiotic.•S. griseochromogenes ATCC 14511T chromosome consists of 10,764,674 bp with 9822 protein coding genes.•52 gene clusters for the biosynthesis of secondary metabolites were identified using antiSMASH, including four gene clusters of nucleoside antibiotics.

ATCC 14511T (=DSM 40499, =NBRC 13413) is a type strain of Streptomyces griseochromogenes. It is known as a producer of nucleoside antibiotic, blasticidin S. In this report we present the complete genome sequence of S. griseochromogenes ATCC 14511T, which consists of 10,764,674 bp with a linear chromosome, 9822 protein-coding genes, 6 rRNA operons, 74 tRNA and 3 sRNA. The genomic analysis revealed that 52 putative gene clusters are involved in the biosynthesis of secondary metabolites, including four gene clusters of nucleoside antibiotics. These gene clusters provide a beneficial source for production of bioactive natural compounds.

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