| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4754301 | Journal of Photochemistry and Photobiology B: Biology | 2017 | 6 Pages |
Abstract
It was observed that ALA-PDT can inactivate F. monophora conidia directly in a concentration-dependent and dose-dependent manner. RAW264.7 was activated indirectly by photodynamically treated conidia. ALA-PDT can enhance the fungicidal ability of RAW264.7 and protect it from Infection-induced apoptosis in an indirect way. ROS generated by photodynamic treated conidia is associated with mitochondrial-related apoptosis in RAW264.7.The results of this investigation demonstrated that ALA-PDT inactivate F. monophora through two way: directly killing F. monophora conidia through ROS-dependent Oxidative damage; activating RAW264.7 in an indirect way.
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Authors
Xiuwen Yi, Cindy Fransisca, Ya He, Yinghui Liu, Sha Lu, Liya He, Liyan Xi,