Purification and efficient refolding process for recombinant tissue-type plasminogen activator derivative (reteplase) using glycerol and Tranexamic acid

Article ID	Journal	Published Year	Pages	File Type
4755006	Process Biochemistry	2017	48 Pages	PDF

Keywords

tris (hydroxymethyl)-aminomethane TXA t-PA PDI TRIS DTT l-Lysine (PubChem CID: 5962)l-Arginine (PubChem CID: 6322)Reteplase CCD Gdn-HCl EDTA Ethylene glycol (PubChem CID: 174)Ethylenediaminetetraacetic acid Urea (PubChem CID: 1176)Tranexamic acid dithiothreitol circular dichroism Response surface methodology RSM Sucrose (PubChem CID: 5988)Central composite design tissue plasminogen activator Luria–Bertani Guanidinium hydrochloride Protein disulphide isomerase optical density Glycerol (PubChem CID: 753)Glycine (PubChem CID: 750)

Related Topics

Physical Sciences and Engineering Chemical Engineering Bioengineering

Purification and efficient refolding process for recombinant tissue-type plasminogen activator derivative (reteplase) using glycerol and Tranexamic acid

Authors

Seyed Babak Mousavi, Ahmad Fazeli, Seyed Abbas Shojaosadati, Mohammad Reza Fazeli, Sameereh Hashemi-Najafabadi,