An efficient super-resolution approach for obtaining isotropic 3-D imaging using 2-D multi-slice MRI

An approach for obtaining both a high-resolution and high-contrast 3D MRI image volume, desirable for image-guided minimally invasive brain surgery, is proposed. Current MRI imaging techniques, especially in situations where contrast requirements dictate use of T2- weighed sequences with long repetition times, do not deliver sufficient resolution in the cross-slice direction. As SRR techniques can be very attractive for obtaining isotropic 3D MRI images from the anisotropic 2D multi-slice volumes, we adopt in this work a MAP super-resolution method with modified regularization parameters. Experiment results demonstrate that resolution enhancement and better edge definition are obtained.