| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4935108 | Schizophrenia Research | 2016 | 8 Pages |
Abstract
Our finding of decreased relative density of GAD-ir neuropil suggests hypofunction of the GABAergic system, particularly in hippocampal CA1 field and STG layer V of patients with paranoid schizophrenia. The finding that antipsychotic medication seems to counterbalance GABAergic hypofunction in schizophrenia patients suggests the possibility of exploring new treatment avenues which target this system.
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Authors
Johann Steiner, Ralf Brisch, Kolja Schiltz, Henrik Dobrowolny, Christian Mawrin, Marta Krzyżanowska, Hans-Gert Bernstein, Zbigniew Jankowski, Katharina Braun, Andrea Schmitt, Bernhard Bogerts, Tomasz Gos,