Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4964797 | Computers in Biology and Medicine | 2017 | 21 Pages |
Abstract
We propose a design strategy for affinity-based biosensors using nanowires for sensing and measuring biomarker concentration in biological samples. Such sensors have been shown to have superior properties compared to conventional biosensors in terms of LOD (limit of detection), response time, cost, and size. However, there are several parameters affecting the performance of such devices that must be determined. In order to solve the design problem, we have developed a comprehensive model based on stochastic transport equations that makes it possible to optimize the sensing behavior.
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science Applications
Authors
Amirreza Khodadadian, Kiarash Hosseini, Ali Manzour-ol-Ajdad, Marjan Hedayati, Reza Kalantarinejad, Clemens Heitzinger,