Article ID Journal Published Year Pages File Type
5008942 Sensors and Actuators B: Chemical 2017 8 Pages PDF
Abstract

•A new ICT/FRET platform was designed for ratiometric fluorescent probes.•The probe has excellent selectivity and anti-interference for sulfite.•The probe can detect endogenous sulfite in HepG2 and L-02 cells.•The probe can preferably target mitochondria.

A new ICT/FRET platform composed of coumarin-hemicyanine dyad was rationally designed for ratiometric fluorescent probes. The platform could concert the spectral overlap and the emission shifts by changing ICT donor. The mitochondria-targeting probe was developed to sense endogenous sulfite in living cells with high selectivity, sensitivity and fast response.

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Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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