Article ID Journal Published Year Pages File Type
5009407 Sensors and Actuators B: Chemical 2017 19 Pages PDF
Abstract
Inventive designs for DNA-based electrochemical sensing are emerging tremendously in recent years. Herein, we report a label free ionic liquid (1-butyl-3-methylimidazolinium tetrafluoroborate) modified nitrogen doped graphene electrode as a potential platform for the electrochemical discrimination of complementary and non-complementary DNA sequences. The proposed platform holds a great promise for the rapid and selective hand-held detection of DNA sequences with a sensitivity and detection limit of 0.202 μA/nM/mm2 and 8.12 nM respectively, without any expensive labeling and cross-hybridization artifacts.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, , , , ,