Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5009407 | Sensors and Actuators B: Chemical | 2017 | 19 Pages |
Abstract
Inventive designs for DNA-based electrochemical sensing are emerging tremendously in recent years. Herein, we report a label free ionic liquid (1-butyl-3-methylimidazolinium tetrafluoroborate) modified nitrogen doped graphene electrode as a potential platform for the electrochemical discrimination of complementary and non-complementary DNA sequences. The proposed platform holds a great promise for the rapid and selective hand-held detection of DNA sequences with a sensitivity and detection limit of 0.202 μA/nM/mm2 and 8.12 nM respectively, without any expensive labeling and cross-hybridization artifacts.
Related Topics
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Authors
Preethi Sukumaran, Thazhe Veettil Vineesh, Sivamathini Rajappa, Chen-Zhong Li, Subbiah Alwarappan,