Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5009480 | Sensors and Actuators B: Chemical | 2017 | 14 Pages |
Abstract
There is a high demand for ultrafast biosensors for industrial and public health applications. However, the performance of existing sensors is often limited by the slow mass transport process in traditional pressure-driven microfluidic devices. In this paper, we show for the first time that acoustic microbubbles trapped in prefabricated cavities in a micro-chamber are capable of enhancing fluid sample mixing that results in faster delivery of target species to the sensor surface. We demonstrate a drastic reduction of sensor response time (up to 21.3-fold) for surface-based nanosensors in presence of resonantly actuated microbubbles. The obtained results are valid in a wide pH (4-10) range and agree well with previous studies.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
Andrea De Vellis, Dmitry Gritsenko, Yang Lin, Zhenping Wu, Xian Zhang, Yayue Pan, Wei Xue, Jie Xu,