Limited view PET reconstruction of tissue radioactivity maps

This paper proposes a state space method for limited view PET reconstruction. Due to the high-level of noise and data-incompletion, prior knowledge is required to guide PET recovery. The compartmental model is used as an evolution equation to regularize the dynamic reconstruction. The continuous–discrete Kalman filter is adopted to calculate the radioactivity value recursively. With tracer kinetic information as prior, the state space approach can obtain a better result compared with the MLEM algorithm. The identifiability of this method is proved by computer synthetic simulation and real phantom experiment on the Hamamatsu SHR-22000PET scanner.