First review on psoriasis severity risk stratification: An engineering perspective

•First review on psoriasis severity risk stratification in engineering perspective.•In-depth examination of the existing literature for all parameters of PASI.•pCAD system for psoriasis severity assessment in large population.•Variety of psoriasis features based on tissue characteristics.•Validation of system in terms of reliability and stability.

Computer-aided diagnosis (CAD) systems have been used for characterization of several dermatologic diseases in the last few years. Psoriasis is a potentially life-threatening skin disease which affects 125 million people worldwide. The paper presents the first state-of-the-art review of technology solicitation in psoriasis along with its current practices, challenges and assessment techniques. The paper also conducts in-depth examination of the existing literature for all clinical parameters of Psoriasis Area and Severity Index (PASI) i.e., area, erythema, scaliness and thickness. We suggest a role of risk assessment using a decision support system for stratification of psoriasis in large populations. A balanced insight has been presented in all the components of the design, namely: feature extraction, feature selection, disease stratification and overall CAD performance evaluation. We conclude that CAD systems are promising for risk stratification and assessment of psoriasis.