| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 505359 | Computers in Biology and Medicine | 2010 | 7 Pages |
Abstract
A mechanochemical relationship between intracellular flow fields of actin and remodeling of actin filaments is important to the realization of cell motility. In this study, to investigate this mechanochemical relationship, we present a mathematical model describing motions of actin filament and remodeling of the filaments in shear flows. We perform simulations of the dynamics of actin filaments remodeled by polymerization, depolymerization, and severing, and investigate contributions of these remodeling processes to effective shear viscosities of the system.
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science Applications
Authors
Yasuhiro Inoue, Takeji Deji, Yoshitaka Shimada, Masaki Hojo, Taiji Adachi,