Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5160035 | Journal of Molecular Structure | 2017 | 29 Pages |
Abstract
A series of (E)-1-(4-morpholinophenyl)-3-(flourosubstitutedphenyl)-prop-2-en-1-one derivatives were synthesized. Anticancer activity of these derivatives 1-7 were determined against HeLa (human uterus carcinoma) and C6 (Rat Brain tumor) cells using BrdU cell proliferataion ELISA assay. And also fluorinated chalcones 1-7 were examined for the inhibitory effect on PKM2, hCA I and CAII enzymes.291
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bedriye Seda KurÅun Aktar, Emine Elçin Oruç-Emre, Ibrahim DemirtaÅ, Ayse Sahin Yaglioglu, Caglar Guler, Sevki Adem, AyÅegül Karaküçük IyidoÄan,