Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5160433 | Journal of Molecular Structure | 2017 | 6 Pages |
Abstract
A novel cyclic oxygen-bridged adduct, ethyl 2-methyl-4-thioxo-3,4,5,6-tetrahydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-11-carboxylate adduct has been synthesized and characterized. Its anticancer activity was investigated using MCF-7 human breast cell line and the results revealed a moderate activity with 223.55 μg/ml IC50 value.157
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Authors
Mohamed M. Ibrahim, Hamdy S. El-Sheshtawy, Maged El-Kemary, Salih Al-Juaid, Mohamed Youssef, Islam H. El-Azab,