Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
517404 | Journal of the American Medical Informatics Association | 2009 | 5 Pages |
Abstract
This study evaluated the performance of an electronic screening (E-screening) method and used it to recruit patients for the NIH sponsored ACCORD trial. Out of the 193 E-screened patients, 125 met the age criterion (“age ⥠40”). For all of these 125 patients, the performance of E-screening was compared with investigator review. E-screening achieved a negative predictive accuracy of 100% (95% CI: 98-100%), a positive predictive accuracy of 13% (95% CI: 6-13%), a sensitivity of 100% (95% CI: 45-100%), and a specificity of 84% (95% CI: 82-84%). The method maximized the use of a patient database query (i.e., excluded ineligible patients with a 100% accuracy and automatically assembled patient information to facilitate manual review of only patients who were classified as “potentially eligible” by E-screening) and significantly reduced the screening burden associated with the ACCORD trial.
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science Applications
Authors
Samir R. MD, MEng, Chunhua PhD, MS, J. Thomas MD, John F. MD, PhD, David MD, MA,