Article ID Journal Published Year Pages File Type
5195 Biocybernetics and Biomedical Engineering 2014 7 Pages PDF
Abstract

In the light of recent advantages in stem cell research and gene based therapies of viral infections, we present a numerical experiment referring to hematopoietic stem cell based therapy of immunosuppressive viral infection. We use a variation of basic mathematical model for impairment of help to simulate immune impairing infection. Next, we increase virus-specific CTL production (as in therapy) in different stages of infection. Obtained results are analyzed and compared with results from recent in vivo experiment.

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Physical Sciences and Engineering Chemical Engineering Bioengineering
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