Article ID Journal Published Year Pages File Type
5212594 Tetrahedron 2017 5 Pages PDF
Abstract

Palladium-catalyzed direct arylation of maleimides via Heck as well as organoboron-mediated Heck-type reactions are developed. These methods offer an approach to a wide variety of biologically interesting 3,4-diarylmaleimide scaffolds from readily accessible starting materials. These approaches led to the feasible one-pot construction of bisaryl-substituted maleimides which have historically been problematic.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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