Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217280 | Tetrahedron | 2013 | 6 Pages |
Abstract
An efficient synthesis of predominantly (E) symmetrical or unsymmetrical 1,2-difluorostilbenes based on the Suzuki-Miyaura palladium-catalyzed cross-coupling reaction of arylboronic acids with predominantly (E)-1,2-dibromo-1,2-difluoroethene in the presence of Cs2CO3 in toluene is described. The reaction preserved the stereochemistry of the building block and performed in good yield independently of the electron-withdrawing or electron-donating character of the substituents.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Said Eddarir, Mohammed Kajjout, Christian Rolando,