| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225549 | Tetrahedron | 2007 | 41 Pages |
Abstract
Hydrolytic kinetic resolution (HKR) developed by Jacobsen has emerged in recent times as a powerful tool to synthesize both terminal epoxides and their corresponding diols in highly enantiomerically pure form. In this review we have covered the application of HKR method for the first time in the synthesis of biologically active compounds.
Keywords
methoxymethylLTB4HmpABOCDHPLAHtrimethylsilylPMBDMFt-butoxycarbonylDIBAL-HTriflatePPTSm-CPBAm-chloroperbenzoic acidN-bromosuccinimideDMPUTBDPSIBXTributylphosphineLiHMDS2,2-Dimethoxypropaneleukotriene-B4tBMETMSp-methoxybenzylpyridinium p-toluenesulfonatep-toluenesulfonylN,N,N′,N′-tetramethylenediamineNBSRCMTMEDADCMTESDMAPDBUTBAFTBDMSTHPtert-butyl1,8-Diazabicyclo[5.4.0]undec-7-eneDMSOethylAcetyl2-Iodoxybenzoic acidAsymmetric epoxidationImidazoleBenzylTetrabutylammonium fluorideTetrahydropyrantert-butyl methyl ethertert-butyldiphenylsilyltert-butyldimethylsilylTriethylsilylt-BuRing-closing metathesisdiisopropylethylaminedimethylaminopyridinedimethylformamideDihydropyranAsymmetric dihydroxylationDIADDiisobutylaluminum hydrideDichloromethaneDimethyl sulfoxideHydrolytic kinetic resolutionTEMPOSynthesisNatural productsBiological activityphenylMoMMEMMethylDIPEAHexamethylphosphoramide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pradeep Kumar, Vasudeva Naidu, Priti Gupta,