Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225820 | Tetrahedron | 2010 | 8 Pages |
Abstract
Several new polyhydroxylated alkaloids including pyrrolidines with a long side chain and 3-(hydroxymethyl) indolizidines were prepared from a common nitrone easily obtained from d-arabinose. In addition, a total synthesis of hyacinthacine A2 has been achieved in five steps and 67.7% overall yield starting from the same d-arabino-derived nitrone. All synthesized compounds have a common structural feature consisting of a pyrrolidine ring with d-arabino configuration.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ignacio Delso, Tomás Tejero, Andrea Goti, Pedro Merino,