Article ID Journal Published Year Pages File Type
5264035 Tetrahedron Letters 2014 21 Pages PDF
Abstract
Strategies have emerged over the past decade to enable the direct functionalization of the remote and inert β-CH bonds of carbonyl compounds. Based on these strategies, a wide collection of novel β-CC bond formation transformations have been developed, including arylation, alkylation, alkenylation, alkynylation, and carbonylation. This review summarizes these recent methods for CC bond formations via direct β-CH functionalization of carbonyl compounds. The scope and limitation of each strategy are also discussed.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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