Article ID Journal Published Year Pages File Type
5270649 Tetrahedron Letters 2011 4 Pages PDF
Abstract

Efficient deprotection of tritylated amines to the corresponding amines mediated by 20 mol % ceric ammonium nitrate [Ce(NH4)2(NO3)6, CAN], 10 equiv of acetic acid and 15 equiv of water in dichloromethane is presented. This method equally worked well in the case of morpholino nucleosides.

Graphical abstractDownload full-size image

Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Ceric ammonium nitrate-mediated detritylation of tritylated amines
Authors
, ,