Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278074 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A new highly efficient one-pot derivatization of medicinally important 9-aminoacridines (9-AA) at the amine position is described. Simple reductive amination and SNAr reaction using easily accessible starting materials give a fast entry to novel 9-AA derivatives for biological screening.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gary Gellerman, Vladimir Gaisin, Tamara Brider,