Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
534326 | Pattern Recognition Letters | 2010 | 9 Pages |
Abstract
Distant repeats between a pair of protein sequences can be exploited to study the various aspects of proteins such as structure–function relationship, disorders due to protein malfunction, evolutionary analysis, etc. An in-depth analysis of the distant repeats would facilitate to establish a stable evolutionary relation of the repeats with respect to their three-dimensional structure. To this effect, an algorithm has been devised to identify the distant repeats in a pair of protein sequences by essentially using the scores of PAM (Percent Accepted Mutation) matrices. The proposed algorithm will be of much use to researchers involved in the comparative study of various organisms based on the amino-acid repeats in protein sequences.
Keywords
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Vision and Pattern Recognition
Authors
R. Sabarinathan, Nirjhar Banerjee, N. Balakrishnan, K. Sekar,