Article ID Journal Published Year Pages File Type
538504 Displays 2015 13 Pages PDF
Abstract

•We summarize state of the art in MEMS based fiber optical microendoscopy for early cancer assessment.•MEMS scanner technology is a key enabling element in miniaturization of microendoscope.•Electrostatic actuation is the most popular mechanism to drive MEMS scanners.

Fiber-optical microendoscopy has recently been an essential medical diagnostic tool for patients in investigating tissues in vivo due to affordable cost, high quality imaging performance, compact size, high-speed imaging, and flexible movement. Microelectromechanical systems (MEMS) scanner technology has been playing a key role in shaping the miniaturization and enabling high-speed imaging of fiber-optical microendoscopy for over 20 years. In this article, both review of MEMS based fiber-optical microendoscopy for optical coherence tomography, confocal, and two-photon imaging will be discussed. These advanced optical endoscopic imaging modalities provide cellular and molecular features with deep tissue penetration enabling guided resections and early cancer assessment.

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