Refractive index imaging from radiative transfer equation-based reconstruction algorithm: Fundamentals

We present the first reconstruction algorithm for refractive index imaging, which is based on the radiative transfer equation (RTE). An objective function is iteratively minimized to find a solution to the problem of inversion of the refractive index field. The function describes the discrepancies of the emerging light measurements on the surface of the sample to be probed with predicted data from the corresponding numerical model. The unknown refractive index field is updated within each reconstruction iteration according to a search direction on the index distribution given by the adjoint model to the RTE. In this paper, emphasis is placed on the theoretical aspects. Preliminary tests are demonstrated on generic phantoms.

Research highlights►Refractive index reconstruction from laser-based imaging; ►Forward model is based on the full radiative transfer equation; ►Backward model is based on the adjoint to the radiative transfer equation