Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5491601 | Magnetic Resonance Imaging | 2017 | 37 Pages |
Abstract
The three-dimension Fast Low Angle SHot Magnetic Resonance Imaging (3D FLASH) sequence has been widely adopted in medical diagnostic imaging because of its availability, simplicity, and high spatial resolution. To improve the quality of structural brain images acquired with the 3D FLASH sequence, we developed a parameter optimization scheme and image inhomogeneity correction methods. The optimal imaging parameters were determined by maximizing gray-matter and white-matter CNR efficiency. Compared to protocols based on published parameters, applying the proposed optimal imaging parameters increased CNR efficiency by >Â 10%. Image inhomogeneity, including signal and CNR inhomogeneity, was corrected by the choice of an optimal flip angle, estimated transmit function, and estimated receive sensitivity. As a result, our optimization and image inhomogeneity correction greatly improved the quality of images acquired with the 3D FLASH sequence.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Jinghua Wang, Lili He, Hairong Zheng, Zhong-Lin Lu,