| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5499332 | Radiation Physics and Chemistry | 2016 | 9 Pages |
Abstract
Methionine is an essential amino acid, unfortunately prone to oxidation. The mechanism of its oxidation by
- OH radicals has been studied for more than 40 years and still remains misunderstood. We have reinvestigated the oxidation of this residue in model peptides, aiming at i) improving the identification of free radicals by the use of more modern quantum chemistry methods; ii) reinvestigating the one-electron reduction potentials as a function of the position in the sequence; iii) identifying the final compounds, which were still unknown; iv) reinvestigating the intramolecular electron transfer (IET) involving this residue.
- OH radicals has been studied for more than 40 years and still remains misunderstood. We have reinvestigated the oxidation of this residue in model peptides, aiming at i) improving the identification of free radicals by the use of more modern quantum chemistry methods; ii) reinvestigating the one-electron reduction potentials as a function of the position in the sequence; iii) identifying the final compounds, which were still unknown; iv) reinvestigating the intramolecular electron transfer (IET) involving this residue.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Debora Scuderi, Jacqueline Bergès, Pedro de Oliveira, Chantal Houée-Levin,