| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5504676 | Biochemical and Biophysical Research Communications | 2017 | 6 Pages |
Abstract
In conclusion, mutant KRAS promotes endosomal degradation in PDAC cell lines, which is impaired by KRAS silencing. Moreover, KRAS silencing activates RAB5A upregulation and drives PDAC subtype-dependent modulation of endosome trafficking.
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Authors
Christian Teske, Christine Schweitzer, Andrea Palamidessi, Daniela E. Aust, Giorgio Scita, Jürgen Weitz, Thilo Welsch,