Article ID Journal Published Year Pages File Type
5505132 Biochemical and Biophysical Research Communications 2017 6 Pages PDF
Abstract
t-PA binds to Lys91 in the MBP NH2-terminal region and Pg binds to Lys122 in the MBP COOH-terminal region. This proximity promotes the activation of Pg by t-PA. The Pm generated may proteolyze MBP, displacing Pm from the surface which then is inhibited by α2-antiplasmin in the vicinity.257
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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