Article ID Journal Published Year Pages File Type
5505680 Biochemical and Biophysical Research Communications 2017 27 Pages PDF
Abstract
An inhibition of AT1R, and simultaneous activation of AT2R using Telmisartan and Compound 21 reduces oxidative stress, hypertension, NF-κ mediated renal inflammation and caspase mediated apoptosis, which could be partly attributed to its ability to regulate PCAF and histone H3 acetylation.236
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Compound 21 and Telmisartan combination mitigates type 2 diabetic nephropathy through amelioration of caspase mediated apoptosis
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