Article ID Journal Published Year Pages File Type
5506422 Biochemical and Biophysical Research Communications 2017 19 Pages PDF
Abstract
This review discusses current knowledge that links altered mitochondrial dynamics with striatal susceptibility in HD. We also highlight how the modulation of mitochondrial function may constitute an attractive therapeutic approach to reduce mHtt-induced toxicity and therefore prevent the selective striatal neurodegeneration.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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