Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5506422 | Biochemical and Biophysical Research Communications | 2017 | 19 Pages |
Abstract
This review discusses current knowledge that links altered mitochondrial dynamics with striatal susceptibility in HD. We also highlight how the modulation of mitochondrial function may constitute an attractive therapeutic approach to reduce mHtt-induced toxicity and therefore prevent the selective striatal neurodegeneration.
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Authors
Marta Cherubini, Silvia Ginés,