| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5506824 | Biochemical and Biophysical Research Communications | 2016 | 4 Pages |
Abstract
Conbercept is an Fc fusion protein with very complicated carbohydrate profiles which must be carefully monitored through manufacturing process. Here, we introduce an optimized fluorescence derivatization high-performance liquid chromatographic method for glycan mapping in conbercept. Compared with conventional glycan analysis method, this method has much better resolution and higher reproducibility making it excellent for product quality control.
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Biochemistry
Authors
Kun Liu, Jian Huang, Delun Luo, Kai Xu, Zhigang Wu, Xun Xu,