Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5507919 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2017 | 14 Pages |
Abstract
These data suggest that AST may be useful as a preventive/therapeutic agent for cardiac dysfunction and myocardial fibrosis.
Keywords
Sirt1HCFsImmunoprecipitateBNPTACsirtuin1R-SmadsTGF-β1percentage fractional shorteningH&EROSAstaxanthinASTImmunoblottingImmunofluorescenceTemTransforming growth factor-β1transverse aortic constrictionCardiac functionhuman cardiac fibroblastsFibrosisTransmission electron microscopeHematoxylin and Eosinbody weightHeart weightbrain natriuretic peptideReactive oxygen species
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Authors
Jun Zhang, Quan-zhen Wang, Shao-hua Zhao, Xiang Ji, Jie Qiu, Jian Wang, Yi Zhou, Qian Cai, Jie Zhang, Hai-qing Gao,