Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5507975 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2017 | 41 Pages |
Abstract
O-mannosyl glycan has a novel, unique structure that is important for the maintenance of brain and muscle functions. These findings have opened up a new field in glycoscience. These studies will further contribute to the understanding of the pathomechanism of α-dystroglycanopathy and the development of glycotherapeutics. This article is part of a Special Issue entitled Neuro-glycoscience, edited by Kenji Kadomatsu and Hiroshi Kitagawa.
Keywords
FKRPProtein O-mannosyltransferasePOMGNT1FKTNXylGlcARBOα-DGCRISPRPNPO-GlycosylationGlcNAcα-dystroglycanp-nitrophenylGlucuronic acidLARGEclustered regularly interspaced short palindromic repeatsMuscular dystrophyribitolFukutinMannoseManN-acetylglucosamineFukutin-related proteinXyloseGlycosyltransferase
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Authors
Hiroshi Manya, Tamao Endo,