Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5507989 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2017 | 9 Pages |
Abstract
The multi-faceted features of the function of ASK1 have been discovered over the past two decades, revealing that ASK1 is a crucial molecule for maintaining cellular homeostasis, especially under conditions of stress. Based on the results that ASK1 deficiency provides beneficial effects for several diseases, modulating ASK1 activity is a promising method to ameliorate a subset of diseases.
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Authors
Chihiro Sakauchi, Hiroaki Wakatsuki, Hidenori Ichijo, Kazuki Hattori,