| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5508014 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2017 | 55 Pages |
Abstract
This concept will help in the search of new drugs that act as senescence-inductors. BA is under evaluation as chemotherapeutic agent against several types of tumors and induction of cell senescence should be considered as one of its main mechanisms of action.
Keywords
DMEMDPPEOISCOXIVAAUCtsBPoPCΔΨmLMPGAPDHFBSCVSDDR1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideDulbecco's modified Eagle's mediumMTTLysosomal membrane permeabilizationBetulinic acidOncogene-Induced SenescenceMembrane biophysicsNeutral redCrystal violet stainingfetal bovine serumcytochrome c oxidase subunit IVSipsDNA damage responseMitochondrial membrane potentialStress-induced premature senescenceCathepsin BChloroquineglyceraldehyde-3-phosphate dehydrogenase
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Biochemistry
Authors
Waleska K. Martins, Andreza B. Gomide, Ãrico T. Costa, Helena C. Junqueira, Beatriz S. Stolf, Rosangela Itri, MaurÃcio S. Baptista,